Blar i NTNU Open på forfatter "Khan, Essa Ahsan"
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Alteration of hepato-lipidomic homeostasis in A/J mice fed an environmentally relevant PFAS mixture
Khan, Essa Ahsan; Grønnestad, Randi; Krøkje, Aase; Bartosova, Zdenka; Johanson, Silje Modahl; Müller, Mette Helen Bjørge; Arukwe, Augustine Ebeku (Peer reviewed; Journal article, 2023)In the present study, we have investigated liver lipid homeostasis and corresponding changes in transcript and functional product levels in A/J mice exposed to environmental relevant concentration of per- and polyfluoroalkyl ... -
Application of quantitative transcriptomics in evaluating the ex vivo effects of per- and polyfluoroalkyl substances on Atlantic cod (Gadus morhua) ovarian physiology
Khan, Essa Ahsan; Zhang, Xiaokang; Hanna, Eileen Marie; Yadetie, Fekadu; Jonassen, Inge; Goksøyr, Anders; Arukwe, Augustine (Peer reviewed; Journal article, 2020)Because of their global consumption and persistence, per- and polyfluoroalkyl substances (PFASs), are ubiquitously distributed in the environment, as well as in wildlife and humans. In the present study, we have employed ... -
Contaminant accumulation and biological responses in Atlantic cod (Gadus morhua) caged at a capped waste disposal site in Kollevåg, Western Norway
Dale, Karina; Müller, Mette Bjørge; Tairova, Zhanna; Khan, Essa Ahsan; Hatlen, Kristin; Grung, Merete; Yadetie, Fekadu; Lille-Langøy, Roger; Blaser, Nello; Skaug, Hans J; Lyche, Jan Ludvig; Arukwe, Augustine; Hylland, Ketil; Karlsen, Odd André; Goksøyr, Anders (Journal article; Peer reviewed, 2019)The aim of this study was to assess whether fish in Kollevåg, a sheltered bay on the western coast of Norway, previously utilized as a waste disposal site, could be affected by environmental contaminants leaking from the ... -
Effects of Exposure Timing on cyp1a Expression, PAH Elimination, and Lipid Utilization in Lumpfish Embryos Exposed to Produced Water
Hansen, Bjørn Henrik; Arukwe, Augustine Ebeku; Knutsen, Hannah Marie; Skarpnord, Kaja Skyrud; Farkas, Julia; Veylit, Lara; Nepstad, Raymond; Khan, Essa Ahsan; Nordtug, Trond; Sørensen, Lisbet (Peer reviewed; Journal article, 2023)Intentional discharges of produced water from oil production platforms to the marine environment contain a complex mixture of toxicants, including polycyclic aromatic hydrocarbons (PAHs). Early life stages of fish are ... -
Microfluidic dual picoinjection based encapsulation of hemoglobin in alginate microcapsules reinforced by a poly(l-lysine)-g-poly(ethylene glycol)
Ahmed, Husnain; Khan, Essa Ahsan; Stokke, Bjørn Torger (Journal article; Peer reviewed, 2022) -
Modulation of neuro-dopamine homeostasis in juvenile female Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances
Khan, Essa Ahsan; Bertotto, Luisa B.; Dale, Karina; Lille-Langøy, Roger; Yadetie, Fekadu; Karlsen, Odd Andre; Goksøyr, Anders; Schlenk, Daniel; Arukwe, Augustine (Journal article; Peer reviewed, 2019)The dopaminergic effect of PAH and PFAS mixtures, prepared according to environmentally relevant concentrations, has been studied in juvenile female Atlantic cod (Gadus morhua). Benzo[a]pyrene, dibenzothiophene, fluorene, ... -
Quantitative transcriptomics, and lipidomics in evaluating ovarian developmental effects in Atlantic cod (Gadus morhua) caged at a capped marine waste disposal site
Khan, Essa Ahsan; Zhang, Xiaokang; Hanna, Eileen Marie; Bartosova, Zdenka; Yadetie, Fekadu; Jonassen, Inge; Goksøyr, Anders; Arukwe, Augustine (Peer reviewed; Journal article, 2020)In the present study, a previously capped waste disposal site at Kollevåg (Norway) was selected to study the effects of contaminant leakage on biomarkers associated with Atlantic cod (Gadus morhua) reproductive endocrinology ... -
Systems toxicology approach for evaluating the effects of contaminants on fish ovarian development and reproductive endocrine physiology: A combination of field-, in vivo and ex vivo studies using Atlantic cod (Gadus morhua)
Khan, Essa Ahsan (Doctoral theses at NTNU, 2021:102, Doctoral thesis, 2021)Human activities contribute a significant amount of contaminants to the natural environment. Polycyclic aromatic hydrocarbons (PAHs) and per- and polyfluoroalkyl substances (PFASs) are example of contaminants that threaten ... -
Toxicity and developmental effects of Arctic fuel oil types on early life stages of Atlantic cod (Gadus morhua)
Hansen, Bjørn Henrik; Nordtug, Trond; Farkas, Julia; Khan, Essa Ahsan; Oteri, Erika; Kvæstad, Bjarne; Faksness, Liv-Guri; Daling, Per Snorre; Arukwe, Augustine (Journal article; Peer reviewed, 2021)Due to the heavy fuel oil (HFO) ban in Arctic maritime transport and new legislations restricting the sulphur content of fuel oils, new fuel oil types are continuously developed. However, the potential impacts of these new ...